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Dynamic NETosis is Carried Out by Live Neutrophils in Human and Mouse Bacterial Abscesses and During Severe Gram-Positive Infection

Neutrophil extracellular traps (NETs) are released, as neutrophils die in vitro, in a process requiring hours, leaving a temporal gap for invasive microbes to exploit. Functional neutrophils undergoing NETosis have not been documented. During Gram-positive skin infections, we directly visualized liv...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Yipp, Bryan G., Petri, Björn, Salina, Davide, Jenne, Craig N., Scott, Brittney N. V., Zbytnuik, Lori D., Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H. Christopher, Malawista, Stephen E., de Boisfleury Chevance, Anne, Zhang, Kunyan, Conly, John, Kubes, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529131/
https://ncbi.nlm.nih.gov/pubmed/22922410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2847
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