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The developmental origins of the mammalian ovarian reserve

The adult mammalian ovary is devoid of definitive germline stem cells. As such, female reproductive senescence largely results from the depletion of a finite ovarian follicle pool that is produced during embryonic development. Remarkably, the crucial nature and regulation of follicle assembly and su...

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Bibliografische gegevens
Gepubliceerd in:Development
Hoofdauteurs: Grive, Kathryn J., Freiman, Richard N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529035/
https://ncbi.nlm.nih.gov/pubmed/26243868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.125211
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