Expression of chicken interleukin-2 by a highly virulent strain of Newcastle disease virus leads to decreased systemic viral load but does not significantly affect mortality in chickens

BACKGROUND: In mammals, interleukin 2 (IL-2) has been shown to decrease replication or attenuate pathogenicity of numerous viral pathogens (herpes simplex virus, vaccinia virus, human respiratory syncytial virus, human immunodeficiency virus) by activating natural killer cells (NK), cytotoxic T lymp...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Susta, Leonardo, Diel, Diego G., Courtney, Sean, Cardenas-Garcia, Stivalis, Sundick, Roy S., Miller, Patti J., Brown, Corrie C., Afonso, Claudio L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528788/
https://ncbi.nlm.nih.gov/pubmed/26253150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0353-x
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