Expression of chicken interleukin-2 by a highly virulent strain of Newcastle disease virus leads to decreased systemic viral load but does not significantly affect mortality in chickens

BACKGROUND: In mammals, interleukin 2 (IL-2) has been shown to decrease replication or attenuate pathogenicity of numerous viral pathogens (herpes simplex virus, vaccinia virus, human respiratory syncytial virus, human immunodeficiency virus) by activating natural killer cells (NK), cytotoxic T lymp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Virol J
Prif Awduron: Susta, Leonardo, Diel, Diego G., Courtney, Sean, Cardenas-Garcia, Stivalis, Sundick, Roy S., Miller, Patti J., Brown, Corrie C., Afonso, Claudio L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528788/
https://ncbi.nlm.nih.gov/pubmed/26253150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0353-x
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