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Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis

BACKGROUND: Mitochondria are key regulators of apoptosis. In response to stress, BH3-only proteins activate pro-apoptotic Bcl2 family proteins Bax and Bak, which induce mitochondrial outer membrane permeabilization (MOMP). While the large-scale mitochondrial release of pro-apoptotic proteins activat...

詳細記述

保存先:
書誌詳細
出版年:Cell Commun Signal
主要な著者: Choe, Sehyo Charley, Hamacher-Brady, Anne, Brady, Nathan Ryan
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528699/
https://ncbi.nlm.nih.gov/pubmed/26253153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0115-9
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