A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity

Acute myeloid leukaemia is characterized by marked inter- and intra-patient heterogeneity, the identification of which is critical for the design of personalized treatments. Heterogeneity of leukaemic cells is determined by mutations which ultimately affect the cell cycle. We have developed and vali...

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Bibliografische gegevens
Gepubliceerd in:J R Soc Interface
Hoofdauteurs: Fuentes-Garí, María, Misener, Ruth, García-Munzer, David, Velliou, Eirini, Georgiadis, Michael C., Kostoglou, Margaritis, Pistikopoulos, Efstratios N., Panoskaltsis, Nicki, Mantalaris, Athanasios
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2015
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528591/
https://ncbi.nlm.nih.gov/pubmed/26040591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0276
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