A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity

Acute myeloid leukaemia is characterized by marked inter- and intra-patient heterogeneity, the identification of which is critical for the design of personalized treatments. Heterogeneity of leukaemic cells is determined by mutations which ultimately affect the cell cycle. We have developed and vali...

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Sparad:
Bibliografiska uppgifter
I publikationen:J R Soc Interface
Huvudupphovsmän: Fuentes-Garí, María, Misener, Ruth, García-Munzer, David, Velliou, Eirini, Georgiadis, Michael C., Kostoglou, Margaritis, Pistikopoulos, Efstratios N., Panoskaltsis, Nicki, Mantalaris, Athanasios
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Royal Society 2015
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528591/
https://ncbi.nlm.nih.gov/pubmed/26040591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0276
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