A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity

Acute myeloid leukaemia is characterized by marked inter- and intra-patient heterogeneity, the identification of which is critical for the design of personalized treatments. Heterogeneity of leukaemic cells is determined by mutations which ultimately affect the cell cycle. We have developed and vali...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Fuentes-Garí, María, Misener, Ruth, García-Munzer, David, Velliou, Eirini, Georgiadis, Michael C., Kostoglou, Margaritis, Pistikopoulos, Efstratios N., Panoskaltsis, Nicki, Mantalaris, Athanasios
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528591/
https://ncbi.nlm.nih.gov/pubmed/26040591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0276
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