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The challenges of modelling antibody repertoire dynamics in HIV infection
Antibody affinity maturation by somatic hypermutation of B-cell immunoglobulin variable region genes has been studied for decades in various model systems using well-defined antigens. While much is known about the molecular details of the process, our understanding of the selective forces that gener...
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| Publicado en: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528423/ https://ncbi.nlm.nih.gov/pubmed/26194760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0247 |
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