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A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy
Autophagy is an essential eukaryotic pathway requiring tight regulation to maintain homeostasis and preclude disease. Using yeast and mammalian cells, we report a conserved mechanism of autophagy regulation by RNA helicase RCK family members in association with the decapping enzyme Dcp2. Under nutri...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Cell Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528364/ https://ncbi.nlm.nih.gov/pubmed/26098573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3189 |
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