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Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells

Extracellular cysteine cathepsins are known to drive cancer progression, but besides degradation of extracellular matrix proteins little is known about their physiological substrates and thus the molecular mechanisms they deploy. One of the major mechanisms used by other extracellular proteases to f...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Sobotič, Barbara, Vizovišek, Matej, Vidmar, Robert, Van Damme, Petra, Gocheva, Vasilena, Joyce, Johanna A., Gevaert, Kris, Turk, Vito, Turk, Boris, Fonović, Marko
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528248/
https://ncbi.nlm.nih.gov/pubmed/26081835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.044628
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