TRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune Cells

Transient receptor potential melastatin 2 (TRPM2) proteins form Ca(2+)-permeable cationic channels that are potently activated by reactive oxygen species (ROS). ROS are produced during immune responses as signaling molecules as well as anti-microbial agents. ROS-sensitive TRPM2 channels are widely e...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Syed Mortadza, Sharifah Alawieyah, Wang, Lu, Li, Dongliang, Jiang, Lin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528159/
https://ncbi.nlm.nih.gov/pubmed/26300888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00407
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