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A Comprehensive Study of Neutralizing Antigenic Sites on the Hepatitis E Virus (HEV) Capsid by Constructing, Clustering, and Characterizing a Tool Box

The hepatitis E virus (HEV) ORF2 encodes a single structural capsid protein. The E2s domain (amino acids 459–606) of the capsid protein has been identified as the major immune target. All identified neutralizing epitopes are located on this domain; however, a comprehensive characterization of antige...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhao, Min, Li, Xiao-Jing, Tang, Zi-Min, Yang, Fan, Wang, Si-Ling, Cai, Wei, Zhang, Ke, Xia, Ning-Shao, Zheng, Zi-Zheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528150/
https://ncbi.nlm.nih.gov/pubmed/26085097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649764
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