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A Comprehensive Study of Neutralizing Antigenic Sites on the Hepatitis E Virus (HEV) Capsid by Constructing, Clustering, and Characterizing a Tool Box

The hepatitis E virus (HEV) ORF2 encodes a single structural capsid protein. The E2s domain (amino acids 459–606) of the capsid protein has been identified as the major immune target. All identified neutralizing epitopes are located on this domain; however, a comprehensive characterization of antige...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhao, Min, Li, Xiao-Jing, Tang, Zi-Min, Yang, Fan, Wang, Si-Ling, Cai, Wei, Zhang, Ke, Xia, Ning-Shao, Zheng, Zi-Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528150/
https://ncbi.nlm.nih.gov/pubmed/26085097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649764
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