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A Comprehensive Study of Neutralizing Antigenic Sites on the Hepatitis E Virus (HEV) Capsid by Constructing, Clustering, and Characterizing a Tool Box

The hepatitis E virus (HEV) ORF2 encodes a single structural capsid protein. The E2s domain (amino acids 459–606) of the capsid protein has been identified as the major immune target. All identified neutralizing epitopes are located on this domain; however, a comprehensive characterization of antige...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Zhao, Min, Li, Xiao-Jing, Tang, Zi-Min, Yang, Fan, Wang, Si-Ling, Cai, Wei, Zhang, Ke, Xia, Ning-Shao, Zheng, Zi-Zheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528150/
https://ncbi.nlm.nih.gov/pubmed/26085097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649764
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