Generating a Metal-responsive Transcriptional Regulator to Test What Confers Metal Sensing in Cells

FrmR from Salmonella enterica serovar typhimurium (a CsoR/RcnR-like transcriptional de-repressor) is shown to repress the frmRA operator-promoter, and repression is alleviated by formaldehyde but not manganese, iron, cobalt, nickel, copper, or Zn(II) within cells. In contrast, repression by a mutant...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Osman, Deenah, Piergentili, Cecilia, Chen, Junjun, Chakrabarti, Buddhapriya, Foster, Andrew W., Lurie-Luke, Elena, Huggins, Thomas G., Robinson, Nigel J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528141/
https://ncbi.nlm.nih.gov/pubmed/26109070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663427
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