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Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily

G-protein-coupled receptors (GPCRs) are frequent and fruitful targets for drug discovery and development, as well as being off-targets for the side effects of a variety of medications. Much of the druggable non-olfactory human GPCR-ome remains under-interrogated, and we present here various approach...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Roth, Bryan L., Kroeze, Wesley K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528112/
https://ncbi.nlm.nih.gov/pubmed/26100629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.654764
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