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Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner.

The regulation of p34cdc2 was investigated by overproducing p34cdc2, cyclin (A and B) and the wee1+ gene product (p107wee1) using a baculoviral expression system. p34cdc2 formed a functional complex with both cyclins as judged by co-precipitation, phosphorylation of cyclin in vitro, and activation o...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Parker, L L, Atherton-Fessler, S, Lee, M S, Ogg, S, Falk, J L, Swenson, K I, Piwnica-Worms, H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850698/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08067.x
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