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The twin drug approach for novel nicotinic acetylcholine receptor ligands
The association of two pharmacophoric entities generates so-called “twin drugs” or dimer derivatives. We applied this approach for the design of a small compound library for the interaction with α4β2* nicotinic acetylcholine receptors (nAChRs). In this compound series, the nAChR ligand N,N-dimethyl-...
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| Publicat a: | Bioorg Med Chem |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527756/ https://ncbi.nlm.nih.gov/pubmed/26142318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.06.034 |
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