Association of CD8 with p56lck is required for early T cell signalling events.

The human CD8 glycoprotein functions as a co-receptor during T cell activation by both binding to MHC class I and transducing a transmembrane signal. The ability of CD8 to transduce a signal is mediated in part by its association with the protein tyrosine kinase p56lck. Using a panel of human CD8 al...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Chalupny, N J, Ledbetter, J A, Kavathas, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452774/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1902413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08061.x
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