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Association of CD8 with p56lck is required for early T cell signalling events.

The human CD8 glycoprotein functions as a co-receptor during T cell activation by both binding to MHC class I and transducing a transmembrane signal. The ability of CD8 to transduce a signal is mediated in part by its association with the protein tyrosine kinase p56lck. Using a panel of human CD8 al...

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Autors principals: Chalupny, N J, Ledbetter, J A, Kavathas, P
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC452774/
https://ncbi.nlm.nih.gov/pubmed/1902413
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