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Structure-function analysis of interleukin-5 utilizing mouse/human chimeric molecules.

Interleukin-5 (IL5) is a T cell derived glycoprotein that stimulates eosinophil production and activation. In the mouse, but apparently not in the human, it is active on B cells. The murine and human IL5 polypeptides exhibit 70% sequence similarity and yet display distinct species-specific activity....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McKenzie, A N, Barry, S C, Strath, M, Sanderson, C J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC452773/
https://ncbi.nlm.nih.gov/pubmed/2022187
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