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Structure-function analysis of interleukin-5 utilizing mouse/human chimeric molecules.

Interleukin-5 (IL5) is a T cell derived glycoprotein that stimulates eosinophil production and activation. In the mouse, but apparently not in the human, it is active on B cells. The murine and human IL5 polypeptides exhibit 70% sequence similarity and yet display distinct species-specific activity....

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: McKenzie, A N, Barry, S C, Strath, M, Sanderson, C J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452773/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08060.x
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