Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis

Langerhans cell histiocytosis (LCH) is a rare disease caused by the clonal accumulation of dendritic Langerhans cells, which is often accompanied by osteolytic lesions. It has been reported that osteoclast-like cells play a major role in the pathogenic bone destruction seen in patients with LCH and...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Grosjean, Frédéric, Nasi, Sonia, Schneider, Pascal, Chobaz, Véronique, Liu, Alexandra, Mordasini, Vanessa, Moullec, Kristell, Vezzoni, Paolo, Lavanchy, Christine, Busso, Nathalie, Acha-Orbea, Hans, Ehirchiou, Driss
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527720/
https://ncbi.nlm.nih.gov/pubmed/26247358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133917
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