Oxa, Thia, Heterocycle, and Carborane Analogues of SQ109: Bacterial and Protozoal Cell Growth Inhibitors

We synthesized a library of 48 analogs of the Mycobacterium tuberculosis cell growth inhibitor SQ109 in which the ethylene diamine linker was replaced by oxa-, thia- or heterocyclic species, and in some cases, the adamantyl group was replaced by a 1,2-carborane or the N-geranyl group by another hydr...

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Bibliographic Details
Published in:ACS Infect Dis
Main Authors: Li, Kai, Wang, Yang, Yang, Gyongseon, Byun, Sooyoung, Rao, Guodong, Shoen, Carolyn, Yang, Hongliang, Gulati, Anmol, Crick, Dean C., Cynamon, Michael, Huang, Guozhong, Docampo, Roberto, No, Joo Hwan, Oldfield, Eric
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527605/
https://ncbi.nlm.nih.gov/pubmed/26258172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00026
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