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Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance

There are two main mechanisms by which cells become multidrug resistant (MDR): by increasing drug efflux pumps on the cell membrane and by increasing anti-apoptotic pathways. The use of nanotechnology to develop nanodelivery systems has allowed researchers to overcome limitations of antineoplastic d...

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Detalhes bibliográficos
Publicado no:Nano Today
Main Authors: Creixell, Mar, Peppas, Nicholas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527553/
https://ncbi.nlm.nih.gov/pubmed/26257819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nantod.2012.06.013
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