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Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO(®) (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers
BACKGROUND: HCP1004 is a newly developed fixed-dose combination of naproxen (500 mg) and esomeprazole strontium (20 mg) that is used in the treatment of rheumatic diseases and can reduce the risk of nonsteroidal anti-inflammatory drug-associated ulcers. The aim of this study was to evaluate the phar...
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發表在: | Drug Des Devel Ther |
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Main Authors: | , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Dove Medical Press
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527374/ https://ncbi.nlm.nih.gov/pubmed/26257511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86725 |
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