Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO(®) (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

BACKGROUND: HCP1004 is a newly developed fixed-dose combination of naproxen (500 mg) and esomeprazole strontium (20 mg) that is used in the treatment of rheumatic diseases and can reduce the risk of nonsteroidal anti-inflammatory drug-associated ulcers. The aim of this study was to evaluate the phar...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: Choi, YoonJung, Han, HyeKyung, Shin, Dongseong, Lim, Kyoung Soo, Yu, Kyung-Sang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527374/
https://ncbi.nlm.nih.gov/pubmed/26257511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86725
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