Retinoic acid-induced CHD5 upregulation and neuronal differentiation of neuroblastoma

BACKGROUND: Chromodomain-helicase DNA binding protein 5 (CHD5) is an important tumor suppressor gene deleted from 1p36.31 in neuroblastomas (NBs). High CHD5 expression is associated with a favorable prognosis, but deletion or low expression is frequent in high-risk tumors. We explored the role of CH...

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Publicat a:Mol Cancer
Autors principals: Higashi, Mayumi, Kolla, Venkatadri, Iyer, Radhika, Naraparaju, Koumudi, Zhuang, Tiangang, Kolla, Sriharsha, Brodeur, Garrett M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527355/
https://ncbi.nlm.nih.gov/pubmed/26245651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0425-y
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