Role of electrostatic interactions for ligand recognition and specificity of peptide transporters

BACKGROUND: Peptide transporters are membrane proteins that mediate the cellular uptake of di- and tripeptides, and of peptidomimetic drugs such as β-lactam antibiotics, antiviral drugs and antineoplastic agents. In spite of their high physiological and pharmaceutical importance, the molecular recog...

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Sparad:
Bibliografiska uppgifter
I publikationen:BMC Biol
Huvudupphovsmän: Boggavarapu, Rajendra, Jeckelmann, Jean-Marc, Harder, Daniel, Ucurum, Zöhre, Fotiadis, Dimitrios
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527243/
https://ncbi.nlm.nih.gov/pubmed/26246134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0167-8
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