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In vitro response pattern of monocytes after tmTNF reverse signaling predicts response to anti-TNF therapy in rheumatoid arthritis

BACKGROUND: Treatment with TNF inhibitors is very efficient in the majority of the patients with rheumatoid arthritis (RA), but it does not achieve a sufficient treatment response in 40–50% of the cases. Goal of the study was to assess functional ex vivo-tests of RA monocytes as prognostic parameter...

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Pubblicato in:J Transl Med
Autori principali: Meusch, Undine, Krasselt, Marco, Rossol, Manuela, Baerwald, Christoph, Klingner, Maria, Wagner, Ulf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527214/
https://ncbi.nlm.nih.gov/pubmed/26251236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0620-z
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