Deficient spontaneous in vitro apoptosis and increased tmTNF reverse signaling-induced apoptosis of monocytes predict suboptimal therapeutic response of rheumatoid arthritis to TNF inhibition

INTRODUCTION: In vitro apoptosis of peripheral monocytes in rheumatoid arthritis (RA) is disturbed and influenced by cytokine production and transmembrane TNF (tmTNF) reverse signaling. The goal of the study was the analysis of the predictive value of the rate of in vitro apoptosis for the therapeut...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Meusch, Undine, Klingner, Maria, Baerwald, Christoph, Rossol, Manuela, Wagner, Ulf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029313/
https://ncbi.nlm.nih.gov/pubmed/24354986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4416
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