Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy

BACKGROUND: Epigenetic variation has been linked to several human diseases. Proliferative diabetic retinopathy (PDR) is a major cause of vision loss in subjects with diabetes. However, studies examining the association between PDR and the genome-wide DNA methylation pattern are lacking. Our aim was...

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Veröffentlicht in:BMC Med
Hauptverfasser: Agardh, Elisabet, Lundstig, Annika, Perfilyev, Alexander, Volkov, Petr, Freiburghaus, Tove, Lindholm, Eero, Rönn, Tina, Agardh, Carl-David, Ling, Charlotte
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527111/
https://ncbi.nlm.nih.gov/pubmed/26248552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0421-5
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