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Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements

Dysfunctional adipose tissue represents a hallmark of type 2 diabetes and systemic insulin resistance, characterized by fibrotic deposition of collagens and increased immune cell infiltration within the depots. Here we generate an inducible model of loss of function of the protein phosphatase and te...

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書目詳細資料
發表在:Nat Commun
Main Authors: Morley, Thomas S., Xia, Jonathan Y., Scherer, Philipp E.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527086/
https://ncbi.nlm.nih.gov/pubmed/26243466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8906
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