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Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements

Dysfunctional adipose tissue represents a hallmark of type 2 diabetes and systemic insulin resistance, characterized by fibrotic deposition of collagens and increased immune cell infiltration within the depots. Here we generate an inducible model of loss of function of the protein phosphatase and te...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Morley, Thomas S., Xia, Jonathan Y., Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527086/
https://ncbi.nlm.nih.gov/pubmed/26243466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8906
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