Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus.

A number of inherited and acquired serum protein deficiencies including hemophilias A and B, diabetes mellitus, and the erythropoietin-responsive anemias are currently treated with repeated subcutaneous or intravenous infusions of purified or recombinant proteins. The development of an in vivo gene-...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Tripathy, S K, Goldwasser, E, Lu, M M, Barr, E, Leiden, J M
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45270/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.24.11557
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