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Array comparative genomic hybridization identifies a heterozygous deletion of exon 3 of the RYR2 gene

BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a heritable cardiac disorder characterized by life-threatening ventricular tachycardia caused by exercise or acute emotional stress. The standard diagnostic screening involves Sanger-based sequencing of 45 of the 105 transla...

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Bibliografske podrobnosti
izdano v:Ups J Med Sci
Main Authors: Leong, Ivone U. S., Sucich, Jennifer, Prosser, Debra O., Skinner, Jonathan R., Crawford, Jackie R., Higgins, Colleen, Love, Donald R.
Format: Artigo
Jezik:Inglês
Izdano: Informa Healthcare 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526874/
https://ncbi.nlm.nih.gov/pubmed/25835811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2015.1029101
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