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αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
PURPOSE: To elucidate the mechanism of the induction of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) by photoreceptor outer segments (POS) and its effects on retinal pigment epithelium (RPE). METHODS: PGC-1α upregulation by POS was confirmed in ARPE-19 cells and in RPE ex viv...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526642/ https://ncbi.nlm.nih.gov/pubmed/26244551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134870 |
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