A selective cyclic integrin antagonist blocks the integrin receptors α(v)β(3 )and α(v)β(5 )and inhibits retinal pigment epithelium cell attachment, migration and invasion

BACKGROUND: Proliferative vitreoretinopathy (PVR) is a leading cause of blindness after failed retinal reattachment surgery. PVR is characterized by the proliferation, migration and contraction of retinal pigmented epithelial cells (RPE), and these cellular responses are influenced by the expression...

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Hlavní autoři: Hoffmann, Stephan, He, Shikun, Jin, Manlin, Ehren, Marianne, Wiedemann, Peter, Ryan, Stephen J, Hinton, David R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184086/
https://ncbi.nlm.nih.gov/pubmed/15987521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-5-16
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