A selective cyclic integrin antagonist blocks the integrin receptors α(v)β(3 )and α(v)β(5 )and inhibits retinal pigment epithelium cell attachment, migration and invasion

BACKGROUND: Proliferative vitreoretinopathy (PVR) is a leading cause of blindness after failed retinal reattachment surgery. PVR is characterized by the proliferation, migration and contraction of retinal pigmented epithelial cells (RPE), and these cellular responses are influenced by the expression...

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Main Authors: Hoffmann, Stephan, He, Shikun, Jin, Manlin, Ehren, Marianne, Wiedemann, Peter, Ryan, Stephen J, Hinton, David R
格式: Artigo
語言:Inglês
出版: BioMed Central 2005
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184086/
https://ncbi.nlm.nih.gov/pubmed/15987521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-5-16
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