A selective cyclic integrin antagonist blocks the integrin receptors α(v)β(3 )and α(v)β(5 )and inhibits retinal pigment epithelium cell attachment, migration and invasion

BACKGROUND: Proliferative vitreoretinopathy (PVR) is a leading cause of blindness after failed retinal reattachment surgery. PVR is characterized by the proliferation, migration and contraction of retinal pigmented epithelial cells (RPE), and these cellular responses are influenced by the expression...

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Библиографические подробности
Главные авторы: Hoffmann, Stephan, He, Shikun, Jin, Manlin, Ehren, Marianne, Wiedemann, Peter, Ryan, Stephen J, Hinton, David R
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2005
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184086/
https://ncbi.nlm.nih.gov/pubmed/15987521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-5-16
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