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An Origin of Cooperative Oxygen Binding of Human Adult Hemoglobin: Different Roles of the α and β Subunits in the α(2)β(2) Tetramer
Human hemoglobin (Hb), which is an α(2)β(2) tetramer and binds four O(2) molecules, changes its O(2)-affinity from low to high as an increase of bound O(2), that is characterized by ‘cooperativity’. This property is indispensable for its function of O(2) transfer from a lung to tissues and is accoun...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526547/ https://ncbi.nlm.nih.gov/pubmed/26244770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135080 |
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