Redeployment of Myc and E2f1-3 drives Rb deficient cell cycles

Robust mechanisms to control cell proliferation have evolved to maintain the integrity of organ architecture. Here, we investigated how two critical proliferative pathways, Myc and E2f, are integrated to control cell cycles in normal and Rb deficient cells using a murine intestinal model. We show th...

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Publicat a:Nat Cell Biol
Autors principals: Liu, Huayang, Tang, Xing, Srivastava, Arunima, Pécot, Thierry, Daniel, Piotr, Hemmelgarn, Benjamin, Reyes, Stephan, Fackler, Nicholas, Bajwa, Amneet, Kladney, Raleigh, Koivisto, Christopher, Chen, Zhong, Wang, Qianben, Huang, Kun, Machiraju, Raghu, Sáenz-Robles, Maria Teresa, Cantalupo, Paul, Pipas, James M., Leone, Gustavo
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526313/
https://ncbi.nlm.nih.gov/pubmed/26192440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3210
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