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Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy

Thermal ablation to destroy tumor tissue may help activate tumor-specific T cells by elevating the presentation of tumor antigens to the immune system. However, the antitumor activity of these T cells may be restrained by their expression of the inhibitory T cell co-receptor CTLA-4, the target of th...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Waitz, Rebecca, Solomon, Stephen B., Petre, Elena N., Trumble, Anne E., Fassò, Marcella, Norton, Larry, Allison, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526218/
https://ncbi.nlm.nih.gov/pubmed/22108823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1782
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