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Hypoxia enhances cholangiocarcinoma invasion through activation of hepatocyte growth factor receptor and the extracellular signal-regulated kinase signaling pathway

Hypoxia is associated with tumor progression and poor prognosis in several cancer types. The present study aimed to examine the contribution of hypoxia (1% O(2)) to cancer progression in a cholangiocarcinoma cell line, RMCCA-1. The molecular basis of the hypoxic response pathway was investigated. Th...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: VANICHAPOL, THITINEE, LEELAWAT, KAWIN, HONGENG, SURADEJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526074/
https://ncbi.nlm.nih.gov/pubmed/26018028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.3865
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