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Intracellular Trafficking of Bile Salt Export Pump (ABCB11) in Polarized Hepatic Cells: Constitutive Cycling between the Canalicular Membrane and rab11-positive Endosomes

The bile salt export pump (BSEP, ABCB11) couples ATP hydrolysis with transport of bile acids into the bile canaliculus of hepatocytes. Its localization in the apical canalicular membrane is physiologically regulated by the demand to secrete biliary components. To gain insight into how such localizat...

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Hlavní autoři: Wakabayashi, Yoshiyuki, Lippincott-Schwartz, Jennifer, Arias, Irwin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC452599/
https://ncbi.nlm.nih.gov/pubmed/15121884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-10-0737
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