Transmembrane Peptides as Inhibitors of ErbB Receptor Signaling

Receptor tyrosine kinases have a single transmembrane (TM) segment that is usually assumed to play a passive role in ligand-induced dimerization and activation of the receptor. However, mutations within some of these receptors, and recent studies with the epidermal growth factor (EGF) and ErbB2 rece...

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Bibliographic Details
Main Authors: Bennasroune, Amar, Fickova, Maria, Gardin, Anne, Dirrig-Grosch, Sylvie, Aunis, Dominique, Crémel, Gérard, Hubert, Pierre
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2004
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452597/
https://ncbi.nlm.nih.gov/pubmed/15146055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-10-0753
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