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The Transcriptional Response to Raf Activation Is Almost Completely Dependent on Mitogen-activated Protein Kinase Kinase Activity and Shows a Major Autocrine Component

The Raf protein kinases are major effectors of Ras GTPases and key components of the transcriptional response to serum factors, acting at least in part through the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway. It has recently been suggested that Raf also may trigger...

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Detalhes bibliográficos
Main Authors: Schulze, Almut, Nicke, Barbara, Warne, Patricia H., Tomlinson, Simon, Downward, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452596/
https://ncbi.nlm.nih.gov/pubmed/15090615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0807
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