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Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments

PURPOSE: Apply manganese-enhanced magnetic resonance imaging (MEMRI) to assess ion channel activity and structure of retinas from mice subject to light-induced retinal degeneration treated with prophylactic agents. METHODS: Abca4(−/−)Rdh8(−/−) double knockout mice with and without prophylactic retin...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Schur, Rebecca M., Sheng, Li, Sahu, Bhubanananda, Yu, Guanping, Gao, Songqi, Yu, Xin, Maeda, Akiko, Palczewski, Krzysztof, Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525634/
https://ncbi.nlm.nih.gov/pubmed/26225634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16522
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