Targeted Multifunctional Lipid ECO Plasmid DNA Nanoparticles as Efficient Non-viral Gene Therapy for Leber’s Congenital Amaurosis

Development of a gene delivery system with high efficiency and a good safety profile is essential for successful gene therapy. Here we developed a targeted non-viral delivery system using a multifunctional lipid ECO for treating Leber’s congenital amaurosis type 2 (LCA2) and tested this in a mouse m...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Sun, Da, Sahu, Bhubanananda, Gao, Songqi, Schur, Rebecca M., Vaidya, Amita M., Maeda, Akiko, Palczewski, Krzysztof, Lu, Zheng-Rong
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363681/
https://ncbi.nlm.nih.gov/pubmed/28624218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.02.005
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker