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Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation

Autophagy is a conserved process that enables catabolic and degradative pathways. Rab family proteins, which are active in the GTP-bound form, regulate the transport and fusion of autophagosomes. However, it remains unclear how each cycle of Rab activation and inactivation is precisely regulated. He...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Toyofuku, Toshihiko, Morimoto, Keiko, Sasawatari, Shigemi, Kumanogoh, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525318/
https://ncbi.nlm.nih.gov/pubmed/26100023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00085-15
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