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Human airway smooth muscle cells secrete amphiregulin via bradykinin/COX-2/PGE(2), inducing COX-2, CXCL8, and VEGF expression in airway epithelial cells
Human airway smooth muscle cells (HASMC) contribute to asthma pathophysiology through an increased smooth muscle mass and elevated cytokine/chemokine output. Little is known about how HASMC and the airway epithelium interact to regulate chronic airway inflammation and remodeling. Amphiregulin is a m...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525120/ https://ncbi.nlm.nih.gov/pubmed/26047642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00390.2014 |
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