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Granzyme B mediated function of Parvovirus B19-specific CD4(+) T cells

A novel conception of CD4(+) T cells with cytolytic potential (CD4(+) CTL) is emerging. These cells appear to have a part in controlling malignancies and chronic infections. Human parvovirus B19 can cause a persistent infection, yet no data exist on the presence of B19-specific CD4(+) CTLs. Such cel...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Kumar, Arun, Perdomo, Maria F, Kantele, Anu, Hedman, Lea, Hedman, Klaus, Franssila, Rauli
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524951/
https://ncbi.nlm.nih.gov/pubmed/26246896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2015.13
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