Llwytho...
Chemical chaperones interfere with the formation of scrapie prion protein.
The fundamental event in prion diseases involves a conformational change in one or more of the alpha-helices of the cellular prion protein (PrP(C)) as they are converted into beta-sheets during the formation of the pathogenic isoform (PrP(Sc)). Here, we show that exposure of scrapie-infected mouse n...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | EMBO J |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
1996
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8978663/ |
| Tagiau: |
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